C3.ai, Inc., TuSimple Holdings Inc., Novavax, Inc. made Friday's list of top gainers.

Leading equity indices in the US rose as S&P 500 closed the day at 4,045.64, having gained 1.61%. Nasdaq ended the session at 11,700 after a 1.97% gain.

Have a look at Friday's biggest gainers:

Novavax | Closed +10.97% at $7.69

Having set a significant high of $83.8 11 months ago, the US biotechnology company is trading 91.73% lower. So far this year, it has been under-performing the Nasdaq by 34.62%. Novavax is currently trading with a market cap of $653.68 million with an average daily volume of 6.68 million shares.

The company reported earnings of -2.28 per share and revenue at $357.40 million. Since the release of its earnings report Tuesday, Novavax lost 11.3%.

+12.15%: TuSimple Holdings gains 12.15% within $1.85 to $2.07 daily range

After closing Friday at $2.03, the self-driving technology developer peaked at $2.07 before giving up early gains and closing at $2.03. TuSimple Holdings's market cap currently stands at $458.19 million with an average daily trading volume of 2.41 million shares. So far this year, it has been beating the Nasdaq by 24.73%.

TuSimple Holdings is scheduled to announce earnings results Wednesday. The consensus Earnings Per Share estimate is -0.58 and the consensus revenue estimate is $2.44 million.

+10.9%: Friday Tuya increased by 10.9%, ended the session at $1.73

After closing at $1.56 on Thursday, Tuya maintained a strong bullish bias that helped the stock close higher at $1.73 Friday. However, market bears ensured the the cloud and management platform provider topped out at $1.76 and that by the end of the session, the market had marked out a distinct $1.58 to $1.76 range. Currently, the cloud and management platform provider has a market capitalization of $1.10 billion with an average daily volume of 724,500 shares. So far this year, it has been doing worse than the Nasdaq by 26.58%.

C3.ai | Closed +33.65% at $28.48

After closing Friday at $28.48, the enterprise AI software provider peaked at $28.94 before giving up early gains and closing at $28.48.

C3.ai released its quarterly earnings report Thursday, beating analysts estimates. The company reported earnings of -0.57 per share on revenue of $66.67 million, topping estimates of -0.69 per share on revenue of $64.24 million. Since the release of its earnings report, C3.ai gained 37.39%.