C3.ai, Inc., TuSimple Holdings Inc., Novavax, Inc. made yesterday's list of top gainers.

Markets were up yesterday; S&P 500 closed the day at 4,045.64, having gained 1.61%. Nasdaq gained 1.97% and closed at 11,700.

More data out yesterday as United States ISM Non-Manufacturing PMI (Feb) released yesterday at 15:00 UTC with a figure of 55.1, while the previous figure was 55.2.

Yesterday was an exciting day for markets with several stocks capitalising on the risk-on mood. Have a look at these Top Gainers:

Novavax | Closed +10.97% at $7.69

Having set a significant high of $83.8 11 months ago, the US biotechnology company is trading 91.73% lower. So far this year, it has been doing worse than the Nasdaq by 34.62%. The company has a market cap of $653.68 million with an average daily volume of 6.68 million shares.

The company reported earnings of -2.28 per share Tuesday, falling short of expectations of -0.92. Revenue was also lower than expected at $357.40 million versus $383.14 million. Since the release of its earnings report, Novavax lost 11.3%

+12.15%: TuSimple Holdings closes at $2.03 after gaining 12.15%

The US holding company topped out at $2.07 having ended yesterday at $2.03. However, despite early momentum, the stock gave up its gains to now trade at $2.03. Currently, the self-driving technology developer has a market capitalization of $458.19 million with an average daily trading volume of 2.41 million shares. So far this year, it has been beating the Nasdaq by 24.73%.

TuSimple Holdings is scheduled to announce earnings results Wednesday. The consensus EPS estimate is -0.58 and the consensus revenue estimate is $2.44 million.

C3.ai | Up 33.65% to $28.48 yesterday

Approximately a day ago, the enterprise-scale AI application developer reached a significant high of $28.48 but has struggled to hold onto its gains and declined 25.18% since then. The enterprise-scale AI application developer's market cap currently stands at $3.14 billion with an average daily trading volume of 32.99 million shares.

C3.ai released its quarterly earnings report Thursday, beating analysts estimates. The company reported earnings of -0.57 per share on revenue of $66.67 million, topping estimates of -0.69 per share on revenue of $64.24 million. Since the release of its earnings report, C3.ai gained 37.39%.