Integra is yesterday's top mover after declining 20.19%

Leading equity indices in the US declined as S&P 500 slipped 1.12% and closed at 4,145.58. Nasdaq closed at 12,560, a 1.26% change.

Today's price action is taking place amid mixed market indicators – United States New Home Sales (Apr) released yesterday at 14:00 UTC with a figure of 683,000, while the previous figure was 656,000.

“Top Movers” are assets that recorded the highest percentage change compared to their nearest peers. yesterday's most active stocks are listed below.

TuSimple Holdings | Up 16.27% to $1.93 yesterday

TuSimple Holdings hit a significant low of 80 cents around 13 days ago, but has since recovered 107.5%. So far this year, it has been beating the Nasdaq by 12.61%. The company has a market cap of $435.62 million with an average daily trading volume of 4 million shares.

Iovance Biotherapeutics is up to $9.22 (+1.77%) in pre-market trading after closing yesterday's session at $9.06

Yesterday's session pointed in the same direction — the US biotech pioneer rose as high as $9.36 before giving up its gains and dropping back to $9.06 before the close on yesterday. Iovance Biotherapeutics's market cap currently stands at $2 billion with an average daily trading volume of 4.85 million shares.

Pre-market trading leads Integra to drop to $38 (a 6.13% change) after ending yesterday at $40.48

After ending Monday at $50.72, Integra LifeSciences Holdings Corporation declined to $39.78 yesterday before closing at $40.48, thereby losing 20.19% in total. The skin regeneration developer's market cap currently stands at $3.32 billion with an average daily volume of 845,429 shares.

HEXO Corp. depreciates 11.89% with $1.25 as the low of the day

Yesterday's session continued down the same path: early in yesterday's session, HEXO Corp. dropped to $1.25 from $1.43 at the end of Monday, before closing at $1.26. During the session, it lost 11.89%. Currently, the high-quality cannabis producer has a market capitalization of $55.44 million with an average daily volume of 326,010 shares.